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Sharkey JT, Cable C, Olcese J

a diuretic medication that appears to lower APOE4 transcription in mice and reduce Alzheimers risk in patients taking it

In contrast with ACE2-modulating medications, we have offered the hypothesis that DPP-4 inhibitors act in prevention/treatment of pulmonary fibrosis, heart, and kidney injury, and since they may be a long-term consequence caused by COVID-19, it is reasonable to expect that DPP-4 inhibitors might be beneficial in alleviating long-term consequences of COVID-19

The 12 mg dose lowered the standard blood-sugar control marker (HbA1c) by approximately 2.0 percentage points at 24 weeks, exceeding dulaglutide's roughly 1.4 percentage point reduction